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zerker barb weapon dilema

Hi guys, I play hcl us east, and this char will be strictly pvm. These are 2 weapons im torn between.

390% ebotd zerk axe or grief runeword

I have a fortiude armour and have a extra Lo rune, so what you guys think i should use. Also what would be the best weapon to put this in.( Hope it is something that can only get 5 sockets)
thanks Loki
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