Voldemort said:
What type of Barb did u use? How many times have you died if u did die?
I am using a pseudo-Titan lance barb. I added 15 to dex to give myself some flexibility with equipment and then every level has been 4 to str, 1 to vit. This gives me just over 2k life (after cries lvl 32) 10k def, just under 80% chance to hit, and 450 str for a whopping 16K WW (Botd eth warpike, lvl 83 might/"Doom" merc, lvl 6 heart of Wolv from wisp projector)
I did not die once (or my merc). The key is to go slow and let the enemys come to you. Don't even have WW on a button when you're in the Chaos Sanctuary or if there are doom knights in the Worldstone Keep. I did reroll the monsters in the halls of vaught once, I walked in and everything on screen was PI and Mana burn, which just wasn't worth it.