What I would recommend is to go around the edge of tristram counter clockwise. Skeletons will probably start popping up on the east side of town. Don't stop and kill skeletons, just keep going north around the edge of town. When you get a chance to lock in on meph without tons of skeletons around him move in and just try to hold the attack button down. I usually have one row of reds, one of blues, and two rows of full rejuvs. Use the full rejuvs when you get a little low prior to life tap kicking in if you aren't using a wand. The mana pots are for when you fight baal. Don't use full rejuvs for mana because he'll probably take all your mana when he hits. The mana pots will keep filling your mana for several seconds even if he drains you completely 2-3 times. You never have to worry about IM (iron maiden) in uber tristram, only when collecting organs. You do have to worry about PI's(physical immunes). There are whiches and ghosts. I use gimmershread on switch and zeal with it against physical immunes. I usually head back to town between ubers to refill pots. Make sure there aren't a bunch of monsters chasing you when you go back via the red portal. Town portals don't work in uber tristram... Excellent job choosing equipment! Good luck!