Just to add my two cents, while smiters aren't exactly the best pvm builds, they're about the only way I can take any of the ubers, particularly chaos tristram... Of course, I'm sure there are some zealots out there who could teach me a thing or two.:dopey:
In PvM, the point of smite is hitting all the time while applying CBs and leeching from Grief's +dmg via lifetap and that's only needed versus Baal and the Ã¼bers. You just need the one point which you invested for being a HS prereq. Other enemies are fought with zeal, so that's the better attack skill in PvM.
PIs are an issue on their own. Either ignore them (which my Enigma zealot does - he has Wizardspike + crap Spirit on the weapon switch for quicker teleportations) or have a weapon in the second slot which works well with Vengeance or deals lots of elemental damage. The bonus from Grief doesn't add to elemental damage from vengeance.