I have no ideaa if this will work. Basically an assasin who uses fully charges tiger strike off monsters and then dragonflights with myrmindon greaves. Probably very impressive damage that could kill players in 1 hit.
I doubt you'll be able to kill somebody in one hit. As far as I remember, the PvP damage penalty is 1/6, so you'd have to do six times the damage of the life of the opponent to kill him, if he has no damage reduction (which most people have at least a bit of). Lets say the average player has 3000 life (barbs/druids will have more, sorcs/necro's will have less). That means you'd have to do 18k damage if that player has NO damage reduction, and you'd have to shoot for at least 25k to be sure to kill them. Then factor in block, chance to miss and such. I don't think it would be reliable.