I can already guess DIII's plot. So what exactly happened, why did Tyrael decided to destroy the Worldstone? My theory is that by destroying the worldstone, as it's pretty obvious that there are going to have 2 factions (Burning Hells and High Heavens), Tyrael would allow the path for the High Heavens to take over the Sanctuary (human's world). Is Tyrael evil ? : No, he's just from another faction, from the Heavens! But no one told Heaven wouldn't try and take over Sanctuary (DIII's concept). Twenty years gap : So, what have demons done for 20 years? They're still not out over all the Sanctuary? I guess they've been fighting Heaven VS Hell style as they're in an eternal war, and both try to take over the Sanctuary. They're simply busy killing eachother. Tyrael is lost ? : So there might be a theory involving that Tyrael is lost. Prior to this, let's assume that there are still two big bosses down in Hell, Azmodan and Belial. They might have captured him, we might have to rescue him. Then, bash the two other demons and then bash Tyrael because at the end we notice that Heaven also tried to take over Sanctuary. Crazy world... Will we fight another Diablo? : This is not possible. Soulstones carry demons. We destroyed Meph's and Big D's soulstone (D's one was destroyed in a cinematic). But what happened to Baal's? If it hasn't been destroyed in the Hellforge, it's still possible that he might revive (however I admit that the explosion at the end of DII:LoD was pretty big and the soulstone could've just been carried away in this...). I'm not going anywhere telling this... just bringing it up. So, in short. DIII: We're going down in hell (or hell comes to us?). Bash hell. Heaven take over. Bash Haven.