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Grief runeword and superior vs unsuperior weapon

Hi all-

A quick question on a smiter. I am building a 1pt smiter/zeal paladin. My ideal weapon is a grief runeword in a 5os zerker axe or phase blade. A quick recap on greif:


35% Chance To Cast Level 15 Venom On Striking

+30-40% Increased Attack Speed (varies)
Damage +340-400 (varies)
Ignore Target's Defense
-25% Target Defense
+(1.875 per character level) 1.875-185.625%
Damage To Demons (Based on Character Level)
Adds 5-30 Fire Damage
-20-25% To Enemy Poison Resistance (varies)
20% Deadly Strike
Prevent Monster Heal
+2 To Mana After Each Kill
+10-15 Life After Each Kill (varies)

Now my question is how the 15% ed of a superior weapon affects the dmg of the runeword. Will it multiply against the base damage of ~35 making a 5dmg difference? or does it multiple off the dmg after the 340-400 is added making it more of a 50-60dmg difference?

Obviously this is important because the difference between the items is 5os phase blade is worth a few pgems and i see 15%ed phase blades going for well over a vex.
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