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Breaking Poison Immunities

Heya heya and well met.

I have been playing a Venomancer for a while now, and noticed that there are quite many poison-immune monsters, which are unaffected by lvl 1 base lower resist.

The question is - is it worth to invest more points to lower? If not, what skills are good for secondary damage or protection after poison is maxed?

Thanks for your time :)
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